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Priftin should not be used once-weekly in the continuation phase regimen in combination with isoniazid inh in hiv-infected patients with active pulmonary tuberculosis because of a higher rate of failure and or relapse with rifampin rif -resistant organisms see warnings and precautions 5.

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the administration of diazepam can be attempted to control seizure activity, but iv pyridoxine is the drug of choice, in a gram-for-isoniazid-ingested-gram dose.

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administer charcoal and sorbitol if within one hour of isoniazid ingestion .

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