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For this reason, all people taking coumarin anticoagulants such as warfarin should have their blood clotting time inr monitored when starting treatment with allopurinol and after any dose increases.

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you should not begin therapy with allopurinol until complete relief of acute attack of gout; during the first month of treatment is recommended prophylactic administration of nsaids or colchicine; in the case of an acute attack of gout during therapy was added to the anti-inflammatory drugs.

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after matching patients on baseline characteristics, a significantly higher proportion of patients taking febuxostat than allopurinol achieved the target sua level at commonly prescribed doses, with approximately 66 more patients achieving sua 5.

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