Detection of this phenotype can be done by approximating erythromycin and clindamycin on an agar plate with a lawn of the organism; a blunting of the zone of inhibition between clindamycin and erythromycin suggests inducible resistance this is known as the d-test .
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strategies to prevent on include screening for chlamydia and gonorrhea during pregnancy and receiving treatment as needed, using erythromycin eye ointment after birth, a wait and see approach in which antibiotics are used only when necessary, using povidone-iodine eye drops after birth when available , or using drops of the mother s first milk after birth.
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uses are same like those of erythromycin but it is preferred for treating otitis media, sinusitis and pneumonia caused by roxithromycin uses, side effects, dosage more practo roxithromycin is used for acute pharyngitis, tonsilitis, sinusitis etc.
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although previously reported as an inhibitor of cyp3a4 based on assumptions inferred from isolated case reports, metronidazole does not significantly inhibit cyp3a4 activity evaluated via erythromycin breath test .
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