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in pediatric patients, the initial dose of prednisolone sodium phosphate oral solution 25 mg prednisolone per 5 ml may vary depending on the specific disease entity being treated.

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many other medicines can interact with methylprednisolone resulting in side effects or changes in the effectiveness of the medications.

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if disease activ-ity persists despite high doses of corticosteroids, one of the following approaches shouldbe considered for rapid control plasmapheresis; intravenous immunoglobulin; or pulsetherapy with high-dose intravenous methylprednisolone.

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in one study, 35 patients with acquired hemophilia and severe bleeding were treated with a combination of cyclophosphamide, prednisolone, large volume immunoadsorption, ivig, and fviii, and treatment appeared to achieve rapid remission in the vast majority of patients.


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